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MinerOss® Block Allograft
MinerOss Block Allograft
MinerOss Block Allograft
MinerOss® Block Allograft is pre-hydrated and ready for immediate implantation using patent pending Aqueous Solution Preservation (ASP). MinerOss® Block Allograft restores bone volume1 and provides an alternative to harvesting an autogenous block graft from the patient therefore eliminating the need for a second surgical procedure.
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applications include
- bone remodeling
- block grafting procedures
- bony defects
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Aqueous Solution Preservation (ASP)
a novel solution for structural bone allowgrafts2,3
Structural musculoskeletal allografts have traditionally been preserved by freeze-drying and packaging in a dry state. While lyophilization imparts a suitable shelf-life, the freeze-drying process has been shown to significantly reduce the mechanical strength and toughness (the energy / work required to fracture) of the grafts.
As such, various hydrated preservation systems have been developed to address this limitation. These hydrated preservation systems negate the need for rehydration prior to implantation, thus facilitating ease and speed of use in the surgical theater. However, leaching of calcium ions from the allografts into the preservation media can degrade the mechanical strength of the grafts over time. This potentially increases the probability of intraoperative and postoperative mechanical failure.
To address this challenge we have developed a novel preservation system (aqueous, isotonic calcium chloride) that inhibits calcium leaching from allografts and preserves maximal strength following processing and subsequent room-temperature storage.
results
Biomechanical testing revealed cervical allografts preserved in ASP display equivalent mechanical strength to frozen grafts and superior mechanical strength to lyophilized grafts.
conclusions
Given the physiological demands structural allografts experience during and after implantation into the cervical, thoracic and lumbar spine as well as for other procedures, it is of the upmost importance to offer grafts with the maximal mechanical strength and toughness (resistance to fracture) to ensure successful clinical outcomes.
The results presented herein reveal that grafts stored in isotonic calcium chloride solution maintain enhanced structural strength and greater toughness as compared to grafts stored in normal saline or subjected to lyophilization. These data suggest the enhanced mechanical properties (strength and toughness) is the result of decreased calcium leaching from the grafts presumably driven by the equilibrium between calcium ions in the solution and within the grafts.
literature
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- Comparison of bone resorption rates after intraoral block bone and guided bone regeneration augmentation for the reconstruction of horizontally deficient maxillary alveolar ridges.
Gultekin B, Bedeloglu E, Kose T, Mijiritsky E. BioMed Research International. 2016: Article ID 4987437 - The Development and Evaluation of a Calcium Chloride Based Preservation Solution for Structural Bone Allografts.
Smith DA, Manda R, Duncan DW, Jenkins PA, Johnson HK, Pierce SL, Schallenberger MA. AATB. 2016, New Orleans, LA. - Effects of preservation and sterilization on cortical bone grafts. A scanning electronic microscope study.
Voggenreiter G, Ascherl R, Blumel G, Schmit-Neuerburg KP. Arch Orthop Trauma Surg. 1994, 113, 294-296.
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Global Headquarters
2300 Riverchase Center
Birmingham, AL 35244
USA
tel: 888.246.8338
tel: 205.967.7880
fax: 205.870.0304
BioHorizons Canada
21 Amber Street, Unit #6
Markham, Ontario L3R 4Z3
Canada
tel: 866.468.8338
fax: 905.944.1894
BioHorizons Chile, S.A.
Av. Manquehue Norte 1337 Office 31
Vitacura
Santiago
Chile
tel: +56 (2) 23619519
fax: +56 (2) 361.9521
BioHorizons Italia Srl
Via Ettore Cristoni, 88
40033 Casalecchio di Reno (BO) Italy
numero verde +800.063.040
tel. +39.051.59.07.00
fax +39.051.57.61.06
BioHorizons Mexico
Cracovia No. 72 Torre B, Oficina: BGO-07, Col. San Ángel
CP: 01000, Ciudad de México, Álvaro Obregón, CDMX
tel. 800 953 0498
Spanish Office
BioHorizons Spain
Calle Oruro, 9
28016 Madrid,
Spain
tel: +34.91.713.10.84
fax: +34.91.355.83.75
BioHorizons Camlog UK & Ireland
Richmond House
Oldbury Road
Bracknell
Berkshire RG12 8TQ
United Kingdom
tel: +44 (0)1344 752560
fax: +44 (0)1344 868049
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